110 http://isa.epfl.ch/imoniteur_ISAP/ itffichecours.txt?path=EPFL.Etu.FicheCours.HeaderFR itffichecours.txt?path=EPFL.Etu.FicheCours.GlobalNav_js fr 2026 3138250313 3138250313 2301874614 2301874614 0 0 Neuro-X NX SV Faculté des sciences de la vie School of Life Sciences !itffichecours.htm?ww_i_matiere=2395755523&ww_x_anneeAcad=2301874614&ww_i_section=3138250313&ww_i_niveau= 1696552884 1696552963 2023-2024 COURSE BOOKLET BIO-480 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease Lecturers Gräff Johannes, Lashuel Hilal, Schneider Bernard Language of teaching English Cursus Computational Neurosciences minor(2023-2024, Mineur : Neurosciences computationnelles 2023-24)
Life Sciences Engineering(2023-2024, SV - Master 2022)
Life Sciences Engineering(2023-2024, SV - Master 2023)
Minor in life sciences engineering (2023-2024, Mineur : Sciences et technologies du vivant 2023-24)
Neuro-X minor(2023-2024, Mineur : Neuro-X 2023-24)
Neuro-X(2023-2024, SNX - Master 2022)
Neuro-X(2023-2024, SNX - Master 2023)
Neuroprosthetics minor(2023-2024, Mineur : Neuroprosthétiques 2023-24)
Neuroscience (edoc)(2023-2024, EDNE 2023-24)
SemesterMand.OptionFilières
x
Hx
MA1, MA3x
MA1, MA3xL
 Credits 5 Session Winter Workload 150h Exam Written Number of positions Semester Fall Weeks 14 Hours 5 weekly
Courses 3 weekly
Exercises 2 weekly
Study planSemesterMand.OptionFilières
EDNE - Neuroscience 2023-24x
Ingénierie des sciences du vivant 2023-24MA1xL
Ingénierie des sciences du vivant 2023-24MA3xL
Mineur : Ingénierie des Sciences du vivant 2023-24Hx
Mineur : Neuro-X 2023-24Hx
Mineur : Neuroprosthétiques 2023-24Hx
Mineur : Neurosciences computationnelles 2023-24Hx
Neuro-X 2023-24MA1x
Neuro-X 2023-24MA3x
Cursus Sem. Type
Computational Neurosciences minor H Opt.
Life Sciences Engineering MA1, MA3 Opt.
Minor in life sciences engineering H Opt.
Neuro-X minor H Opt.
Neuro-X MA1, MA3 Opt.
Neuroprosthetics minor H Opt.
Neuroscience Opt.
Summary The goal of the course is to guide students through the essential aspects of molecular neuroscience and neurodegenerative diseases. The student will gain the ability to dissect the molecular basis of disease in the nervous system in order to begin to understand and identify therapeutic strategies. Content

 

  • Anatomical and functional organization of the brain
  • Unique biology of neurons
  • Unique biology of glial cells
  • Generation, survival and integration of nerve cells
  • Synapse formation, regeneration and plasticity
  • Neuropharmacology
  • Alzheimer's disease
  • Parkinson's disease
  • Motor neuron diseases
  • Prion diseases
  • Polyglutamine expansion diseases
  • Protein aggregation in neurodegenerative disease
  • Animal models of disease and translational neuroscience
  • Neuroepigenetics
 Learning Outcomes By the end of the course, the student must be able to:
  • Define key concepts in neurodegenerative diseases
  • Assess / Evaluate novel therapeutic strategies for neurodegenerative diseases
  • Compare the unique properties of neuronal and glial cells
  • Hypothesize therapeutic strategies for treating brain diseases
  • Describe he function of genes associated with neurodegenerative diseases
  • Design experiments to evaluate genetic mutations associated with neurodegenerative diseases
 Transversal skills
  • Access and evaluate appropriate sources of information.
  • Summarize an article or a technical report.
 Assessment methods

Written exam. 3 hours duration. Will contain short essay-style questions.

 Resources Bibliography

Purves, Neuroscience. 2012. 5th Ed. Sinauer Associates

Kandel, Principles of Neural Science. 2012. 5th Ed. McGraw Hill

Ressources en bibliothèque

 Ressources en bibliothèque
  • Kandel, Principles of Neural Science. 2012. 6th Ed. McGraw Hillhttp://library.epfl.ch/en/beast?isbn=9781259642234
  • Purves, Neuroscience. 2012. 5th Ed. Sinauer Associateshttp://library.epfl.ch/en/beast?isbn=0878936955
Moodle Link Ingénierie des sciences du vivant, 2023-2024, Master semestre 1 Life Sciences Engineering, 2023-2024, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Master semestre 1 MA1 HIVER Master semester 1 MA1 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
L optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Ingénierie des sciences du vivant, 2023-2024, Master semestre 3 Life Sciences Engineering, 2023-2024, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Master semestre 3 MA3 HIVER Master semester 3 MA3 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
L optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Neuro-X, 2023-2024, Master semestre 1 Neuro-X, 2023-2024, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Master semestre 1 MA1 HIVER Master semester 1 MA1 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Neuro-X, 2023-2024, Master semestre 3 Neuro-X, 2023-2024, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Master semestre 3 MA3 HIVER Master semester 3 MA3 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Mineur en Ingénierie des Sciences du Vivant, 2023-2024, Semestre automne Minor in life sciences engineering , 2023-2024, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Semestre automne H HIVER Autumn semester H Mineur en Ingénierie des Sciences du Vivant MIN_SV Minor in life sciences engineering MIN_SV
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Mineur en Neuro-X, 2023-2024, Semestre automne Neuro-X minor, 2023-2024, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Semestre automne H HIVER Autumn semester H Mineur en Neuro-X MIN_NX Neuro-X minor MIN_NX
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Mineur en Neuroprosthétiques, 2023-2024, Semestre automne Neuroprosthetics minor, 2023-2024, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Semestre automne H HIVER Autumn semester H Mineur en Neuroprosthétiques MIN_NEUPRO Neuroprosthetics minor MIN_NEUPRO
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Mineur en Neurosciences computationnelles, 2023-2024, Semestre automne Computational Neurosciences minor, 2023-2024, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Semestre automne H HIVER Autumn semester H Mineur en Neurosciences computationnelles MIN_NEUR_COMP Computational Neurosciences minor MIN_NEUR_COMP
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
Neurosciences (edoc), 2023-2024 Neuroscience (edoc), 2023-2024 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2023-2024 Neurosciences (edoc) EDNE Neuroscience (edoc) EDNE
optionnel optional
3 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Schneider Bernard 150348
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Gräff Johannes 240725
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Lashuel Hilal 167337
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease 5
Ecrit Written Crédit Credits 5 Session hiver Session winter HIV HIV
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HTML_fin JS_debut \x26#961; JS_fin CODE140504636 BOOLEAN_Symbol 1 BaliseJS_debut \x5bRHO\x5d BaliseJS_fin Balise_debut [RHO] Balise_fin FO_debut [inline]=&#929; FO_fin HTML_debut &#929; HTML_fin JS_debut \x26#929; JS_fin CODE148292791 BOOLEAN_Symbol BaliseJS_debut \x5bepsilon\x5d BaliseJS_fin Balise_debut [epsilon] Balise_fin FO_debut [inline]=&#949; FO_fin HTML_debut &#949; HTML_fin JS_debut \x26#949; JS_fin CODE169976220 BOOLEAN_Symbol BaliseJS_debut \x5blig\x5d BaliseJS_fin Balise_debut [lig] Balise_fin FO_debut [inline]=&#x203A;&#160;&#160; FO_fin HTML_debut &#x203A;&#160;&#160; HTML_fin JS_debut \x26#x203A;\x26#160;\x26#160; JS_fin CODE148292899 BOOLEAN_Symbol BaliseJS_debut \x5bEPSILON\x5d BaliseJS_fin Balise_debut [EPSILON] Balise_fin FO_debut [inline]=&#917; FO_fin HTML_debut &#917; HTML_fin JS_debut \x26#917; JS_fin BALISETXT_SAUT BOOLEAN_Symbol BaliseJS_debut \x5bbr\x2f\x5d BaliseJS_fin Balise_debut [br/] Balise_fin FO_debut FO_fin HTML_debut <br/> HTML_fin JS_debut \x3cbr\x2f\x3e JS_fin 2395755523 Neuroscience: from molecular mechanisms to disease Neuroscience: from molecular mechanisms to disease anglais Lashuel Hilal 167337 Schneider Bernard 150348 Gräff Johannes 240725 3138250313