110 http://isa.epfl.ch/imoniteur_ISAP/ itffichecours.txt?path=EPFL.Etu.FicheCours.HeaderFR itffichecours.txt?path=EPFL.Etu.FicheCours.GlobalNav_js fr 2026 2140391 2140391 2840683608 2840683608 1 0 Neurosciences (edoc) EDNE !itffichecours.htm?ww_i_matiere=3150386813&ww_x_anneeAcad=2840683608&ww_i_section=2140391&ww_i_niveau= 1696552884 1696552963 2025-2026 COURSE BOOKLET NX-421 Neural signals and signal processing Neural signals and signal processing Lecturers Micera Silvestro, Van De Ville Dimitri Language of teaching English Cursus Biomedical technologies minor(2025-2026, Mineur : Technologies biomédicales 2025-26)
Computational biology minor(2025-2026, Mineur : Computational Biology 2024-25)
Life Sciences Engineering(2025-2026, SV - Master 2024)
Life Sciences Engineering(2025-2026, SV - Master 2025)
Microengineering(2025-2026, MT - Master 2024)
Microengineering(2025-2026, MT - Master 2025)
Minor in Imaging(2025-2026, Mineur : Imaging 2025-26)
Neuro-X minor(2025-2026, Mineur : Neuro-X 2025-26)
Neuro-X(2025-2026, SNX - Master 2024)
Neuro-X(2025-2026, SNX - Master 2025)
Neuroscience (edoc)(2025-2026, EDNE 2025-26)
Robotics(2025-2026, MT_RO - Master 2024)
Robotics(2025-2026, MT_RO - Master 2025)
SemesterMand.OptionFilières
x
Hx
MA1, MA3x
MA1, MA3xB
MA1, MA3xL
 Credits 6 Session Winter Workload 180h Exam Written Number of positions Semester Fall Weeks 14 Hours 6 weekly
Courses 4 weekly
Exercises 2 weekly
Study planSemesterMand.OptionFilières
EDNE - Neuroscience 2025-26x
Ingénierie des sciences du vivant 2025-26MA1xL
Ingénierie des sciences du vivant 2025-26MA3xL
Microtechnique 2025-26MA1x
Microtechnique 2025-26MA3x
Mineur : Computational biology 2025-26Hx
Mineur : Imaging 2025-26Hx
Mineur : Neuro-X 2025-26Hx
Mineur : Technologies biomédicales 2025-26Hx
Neuro-X 2025-26MA1x
Neuro-X 2025-26MA3x
Robotique 2025-26MA1xB
Robotique 2025-26MA3xB
Cursus Sem. Type
Biomedical technologies minor H Opt.
Computational biology minor H Opt.
Life Sciences Engineering MA1, MA3 Opt.
Microtechnics MA1, MA3 Opt.
Minor in Imaging H Opt.
Neuro-X minor H Opt.
Neuro-X MA1, MA3 Opt.
Neuroscience Obl.
Robotics MA1, MA3 Opt.
Summary Understanding, processing, and analysis of signals and images obtained from the central and peripheral nervous system Content

Understanding neural signals obtained by electrophysiology and imaging techniques requires knowledge both about their origin and the measurement process. This course will introduce the properties of a wide range of neural signals that are used to study the brain in health and disease. The relevance of these signals for applications in fundamental and clinical neuroscience will be made clear. In addition, a broad range of signal processing tools and their implementations will be presented with the specific focus to implement and tailor analysis of these signals, which typically comes as large, noisy, but richly structured datasets. Exercises and lab exercises will provide insights into the analysis of imaging data and electrophysiological neural signals.

 Keywords

Electrophysiology, nervous system, neuroimaging, brain mapping, systems-level neuroscience, MRI

 Learning Prerequisites Required courses

Mathematics at the engineering level (i.e., matrix algebra, probability theory)

Basic signal processing, statistics, and machine-learning concepts

Basic knowledge of programming

 Learning Outcomes By the end of the course, the student must be able to:
  • Analyze processing steps of neural signals and imaging data
  • Assemble a neural data processing pipeline
  • Critique suitability of analysis methods
  • Interpret results of neural signals analysis
  • Explain choice of methodology
 Transversal skills
  • Use a work methodology appropriate to the task.
  • Make an oral presentation.
  • Give feedback (critique) in an appropriate fashion.
 Teaching methods

Weekly lectures (4h) and weekly exercise session (2h)

Mini-projects during the semester

 Expected student activities

Attendance at lectures and exercises

 Assessment methods

Attendance and completion of mini-projects with presentations

Written exam

 Supervision Office hours Yes Assistants Yes Forum Yes Resources Virtual desktop infrastructure (VDI) Yes Bibliography
  • H. Op de Beeck, C. Nakatani, "Introduction to Human Neuroimaging", Cambridge University Press, 2019.
  • N. V. Thakor, "Handbook of Neuroengineering", Springer, 2020.
 Ressources en bibliothèque
  • Find the references at the Libraryhttps://slsp-epfl.primo.exlibrisgroup.com/discovery/search?query=course_code,contains,%22NX-421%202025-2026%22&tab=41SLSP_EPF_MyInst_and_CI&search_scope=MyInst_and_CI&vid=41SLSP_EPF:prod
 Moodle Link Neuro-X, 2025-2026, Master semestre 1 Neuro-X, 2025-2026, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 1 MA1 HIVER Master semester 1 MA1 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Neuro-X, 2025-2026, Master semestre 3 Neuro-X, 2025-2026, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 3 MA3 HIVER Master semester 3 MA3 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Ingénierie des sciences du vivant, 2025-2026, Master semestre 1 Life Sciences Engineering, 2025-2026, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 1 MA1 HIVER Master semester 1 MA1 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
L optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Ingénierie des sciences du vivant, 2025-2026, Master semestre 3 Life Sciences Engineering, 2025-2026, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 3 MA3 HIVER Master semester 3 MA3 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
L optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Microtechnique, 2025-2026, Master semestre 1 Microengineering, 2025-2026, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 1 MA1 HIVER Master semester 1 MA1 Microtechnique MT Microengineering MT
Microtechnique MT Microengineering MT
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Microtechnique, 2025-2026, Master semestre 3 Microengineering, 2025-2026, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 3 MA3 HIVER Master semester 3 MA3 Microtechnique MT Microengineering MT
Microtechnique MT Microengineering MT
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Robotique, 2025-2026, Master semestre 1 Robotics, 2025-2026, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 1 MA1 HIVER Master semester 1 MA1 Robotique MT_RO Robotics MT_RO
Microtechnique MT Microengineering MT
B optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Robotique, 2025-2026, Master semestre 3 Robotics, 2025-2026, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Master semestre 3 MA3 HIVER Master semester 3 MA3 Robotique MT_RO Robotics MT_RO
Microtechnique MT Microengineering MT
B optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Mineur en Computational biology, 2025-2026, Semestre automne Computational biology minor, 2025-2026, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Semestre automne H HIVER Autumn semester H Mineur en Computational biology MIN_IN_COMP_BIO Computational biology minor MIN_IN_COMP_BIO
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Mineur en Imaging, 2025-2026, Semestre automne Minor in Imaging, 2025-2026, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Semestre automne H HIVER Autumn semester H Mineur en Imaging MIN_IMG Minor in Imaging MIN_IMG
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Mineur en Neuro-X, 2025-2026, Semestre automne Neuro-X minor, 2025-2026, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Semestre automne H HIVER Autumn semester H Mineur en Neuro-X MIN_NX Neuro-X minor MIN_NX
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Mineur en Technologies biomédicales, 2025-2026, Semestre automne Biomedical technologies minor, 2025-2026, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Semestre automne H HIVER Autumn semester H Mineur en Technologies biomédicales MIN_BIOMED Biomedical technologies minor MIN_BIOMED
optionnel optional
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
Neurosciences (edoc), 2025-2026 Neuroscience (edoc), 2025-2026 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2025-2026 Neurosciences (edoc) EDNE Neuroscience (edoc) EDNE
obligatoire mandatory
4 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
2 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Micera Silvestro 218366
Génie électrique et électronique EL Electrical and Electronics Engineering EL
Van De Ville Dimitri Nestor Alice 152027
Microtechnique MT Microengineering MT
3150386813 Neural signals and signal processing Neural signals and signal processing 6
Ecrit Written Crédit Credits 6 Session hiver Session winter HIV HIV
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FO_fin HTML_debut &#951; HTML_fin JS_debut \x26#951; JS_fin CODE72092805 BOOLEAN_Symbol BaliseJS_debut \x5bETA\x5d BaliseJS_fin Balise_debut [ETA] Balise_fin FO_debut [inline]=&#919; FO_fin HTML_debut &#919; HTML_fin JS_debut \x26#919; JS_fin BALISE_SOULIGNER BOOLEAN_Symbol BaliseJS_debut \x5bu\x5d BaliseJS_fin \x5b\x2fu\x5d Balise_debut [u] Balise_fin [/u] FO_debut text-decoration=underline FO_fin text-decoration=none HTML_debut <u> HTML_fin </u> JS_debut \x3cu\x3e JS_fin \x3c\x2fu\x3e CODE72092388 BOOLEAN_Symbol BaliseJS_debut \x5bpsi\x5d BaliseJS_fin Balise_debut [psi] Balise_fin FO_debut [inline]=&#968; FO_fin HTML_debut &#968; HTML_fin JS_debut \x26#968; JS_fin CODE72092541 BOOLEAN_Symbol BaliseJS_debut \x5bPSI\x5d BaliseJS_fin Balise_debut [PSI] Balise_fin FO_debut [inline]=&#936; FO_fin HTML_debut &#936; HTML_fin JS_debut \x26#936; JS_fin CODE140502511 BOOLEAN_Symbol 1 BaliseJS_debut \x5brho\x5d BaliseJS_fin Balise_debut [rho] Balise_fin FO_debut [inline]=&#961; FO_fin HTML_debut &#961; HTML_fin JS_debut \x26#961; JS_fin CODE140504636 BOOLEAN_Symbol 1 BaliseJS_debut \x5bRHO\x5d BaliseJS_fin Balise_debut [RHO] Balise_fin FO_debut [inline]=&#929; FO_fin HTML_debut &#929; HTML_fin JS_debut \x26#929; JS_fin CODE148292791 BOOLEAN_Symbol BaliseJS_debut \x5bepsilon\x5d BaliseJS_fin Balise_debut [epsilon] Balise_fin FO_debut [inline]=&#949; FO_fin HTML_debut &#949; HTML_fin JS_debut \x26#949; JS_fin CODE169976220 BOOLEAN_Symbol BaliseJS_debut \x5blig\x5d BaliseJS_fin Balise_debut [lig] Balise_fin FO_debut [inline]=&#x203A;&#160;&#160; FO_fin HTML_debut &#x203A;&#160;&#160; HTML_fin JS_debut \x26#x203A;\x26#160;\x26#160; JS_fin CODE148292899 BOOLEAN_Symbol BaliseJS_debut \x5bEPSILON\x5d BaliseJS_fin Balise_debut [EPSILON] Balise_fin FO_debut [inline]=&#917; FO_fin HTML_debut &#917; HTML_fin JS_debut \x26#917; JS_fin BALISETXT_SAUT BOOLEAN_Symbol BaliseJS_debut \x5bbr\x2f\x5d BaliseJS_fin Balise_debut [br/] Balise_fin FO_debut FO_fin HTML_debut <br/> HTML_fin JS_debut \x3cbr\x2f\x3e JS_fin 3150386813 Neural signals and signal processing Neural signals and signal processing anglais Van De Ville Dimitri Nestor Alice 152027 Micera Silvestro 218366 2140391