110 http://isa.epfl.ch/imoniteur_ISAP/ itffichecours.txt?path=EPFL.Etu.FicheCours.HeaderFR itffichecours.txt?path=EPFL.Etu.FicheCours.GlobalNav_js fr 2026 84482813 2936286 84482813 2305107546 2305107546 0 1 Mineurs MINEUR !itffichecours.htm?ww_i_matiere=839100255&ww_x_anneeAcad=2305107546&ww_i_section=84482813&ww_i_niveau=2936286 1696552884 1696552963 2024-2025 COURSE BOOKLET BIOENG-445 Biomedical optics Biomedical optics Lecturers Wagnières Georges Language of teaching English Cursus Biomedical technologies minor(2024-2025, Mineur : Technologies biomédicales 2024-25)
Life Sciences Engineering(2024-2025, SV - Master 2023)
Life Sciences Engineering(2024-2025, SV - Master 2024)
Microengineering(2024-2025, MT - Master 2023)
Microengineering(2024-2025, MT - Master 2024)
Neuro-X minor(2024-2025, Mineur : Neuro-X 2024-25)
Neuro-X(2024-2025, SNX - Master 2023)
Neuro-X(2024-2025, SNX - Master 2024)
Photonics (edoc)(2024-2025, EDPO 2024-25)
Photonics minor(2024-2025, Photonics 2024-25)
SemesterMand.OptionFilières
x
Hx
MA1, MA3x
MA1, MA3xA
MA1, MA3xB
 Credits 3 Session Winter Workload 90h Exam Oral Number of positions Semester Fall Weeks 14 Hours 3 weekly
Courses 2 weekly
Exercises 1 weekly
Study planSemesterMand.OptionFilières
EDPO - Photonics 2024-25x
Ingénierie des sciences du vivant 2024-25MA1xB
Ingénierie des sciences du vivant 2024-25MA3xB
Microtechnique 2024-25MA1xA
Microtechnique 2024-25MA3xA
Mineur : Neuro-X 2024-25Hx
Mineur : Technologies biomédicales 2024-25Hx
Minor : Photonics 2024-25Hx
Neuro-X 2024-25MA1x
Neuro-X 2024-25MA3x
Cursus Sem. Type
Biomedical technologies minor H Opt.
Life Sciences Engineering MA1, MA3 Opt.
Microtechnics MA1, MA3 Opt.
Neuro-X minor H Opt.
Neuro-X MA1, MA3 Opt.
Photonics minor H Opt.
Photonics Opt.
Summary This course addresses the principles governing the interactions between light and biological tissue, their optical properties and basic concepts of radiometry. Illustrative diagnostic and therapeutic applications of light in medicine and photobiology will also be described. Content

Introduction
Brief history
Introduction to general optics and tissue optics
Radiometry and Photometry
Light dosimetry
Light-tissues interactions
Introduction to molecular spectroscopy
Photosensitizers
Principles and techniques
Absorption, fluorescence and vibrational spectroscopies and imaging.
Time-resolved spectroscopy and imaging.
Light sources, detectors and optical systems.
Applications
Analytical techniques, oxymetry, optical biosensors, Photodetection of early cancers with exogenous and endogenous dyes, Angiography, Phototherapy and Photodynamic therapy, optical coherence tomography.

 Keywords

Biomedical photonics, tissue optics, light-tissue interactions, photodiagnosis, phototherapy, light dosimetry, dyes, photosensitizers.

 Learning Prerequisites Important concepts to start the course

Basic background in biology, chemistry and optics.

 Learning Outcomes
  • Design simple systems used for phototherapy and photodiagnosis.
  • Characterize the spectral design of apparatus used in biomedical optics.
  • Compute the light dose in biological tissues.
  • Identify the optical components to develop an apparatus used in phototherapy.
  • Explain the working principles of apparatus used in biomedical optics.
  • Model the propagation of light in biological tissues.
  • Quantify the light dose in phototherapy.
  • Interpret data obtained or published in photomedicine.
  • Design simple systems used for phototherapy and photodiagnosis.
  • Characterize the spectral design of apparatus used in biomedical optics.
  • Compute the light dose in biological tissues.
  • Identify the optical components to develop an apparatus used in phototherapy.
  • Explain the working principles of apparatus used in biomedical optics.
  • Model the propagation of light in biological tissues.
  • Quantify the light dose in phototherapy.
  • Interpret data obtained or published in photomedicine.
 Transversal skills
  • Access and evaluate appropriate sources of information.
  • Collect data.
  • Make an oral presentation.
  • Summarize an article or a technical report.
  • Communicate effectively with professionals from other disciplines.
 Teaching methods

Lectures, Exercises, recent literature review papers, classroom discussion + oral presentation.

 Expected student activities

Exercises, lecture of review papers, classroom discussion + oral presentation.

 Assessment methods

Oral exam (1/2) + presentation (3/8) + exercices (1/8).

 Supervision Office hours Yes Assistant.e.s Yes Forum No Resources Bibliography Ressources en bibliothèque
  • Optics / Hechthttp://library.epfl.ch/en/beast?isbn=9781292096964
  • Optical-Thermal Response of Laser Irradiated Tissue / Welchhttp://library.epfl.ch/en/beast?isbn=9789048188307
  • Handbook of Photomedicine / Hamblinhttp://library.epfl.ch/en/beast?isbn=9781439884690
  • Principles of Fluorescence Spectroscopy / Lakowiczhttp://library.epfl.ch/en/beast?isbn=9780387312781
  • Photosensitisers in Biomedicine / Wainwrighthttp://library.epfl.ch/en/beast?isbn=9780470744949
  • Quantitative Biomedical Optics / Bigiohttp://library.epfl.ch/en/beast?isbn=9780521876568
  • Handbook of Biomedical Fluorescence / Mycekhttp://library.epfl.ch/en/beast?isbn=0824709551
 Notes/Handbook

Slides available on Moodle.

 Moodle Link Prerequisite for

Master. Academic research and R/D activities in the industry of this field

 Ingénierie des sciences du vivant, 2024-2025, Master semestre 1 Life Sciences Engineering, 2024-2025, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 1 MA1 HIVER Master semester 1 MA1 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
B optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Ingénierie des sciences du vivant, 2024-2025, Master semestre 3 Life Sciences Engineering, 2024-2025, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 3 MA3 HIVER Master semester 3 MA3 Ingénierie des sciences du vivant SV Life Sciences Engineering SV
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
B optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Microtechnique, 2024-2025, Master semestre 1 Microengineering, 2024-2025, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 1 MA1 HIVER Master semester 1 MA1 Microtechnique MT Microengineering MT
Microtechnique MT Microengineering MT
A optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Microtechnique, 2024-2025, Master semestre 3 Microengineering, 2024-2025, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 3 MA3 HIVER Master semester 3 MA3 Microtechnique MT Microengineering MT
Microtechnique MT Microengineering MT
A optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Neuro-X, 2024-2025, Master semestre 1 Neuro-X, 2024-2025, Master semester 1 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 1 MA1 HIVER Master semester 1 MA1 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Neuro-X, 2024-2025, Master semestre 3 Neuro-X, 2024-2025, Master semester 3 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Master semestre 3 MA3 HIVER Master semester 3 MA3 Neuro-X NX Neuro-X NX
Neuro-X NX Neuro-X NX
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Mineur en Neuro-X, 2024-2025, Semestre automne Neuro-X minor, 2024-2025, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Semestre automne H HIVER Autumn semester H Mineur en Neuro-X MIN_NX Neuro-X minor MIN_NX
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Mineur en Technologies biomédicales, 2024-2025, Semestre automne Biomedical technologies minor, 2024-2025, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Semestre automne H HIVER Autumn semester H Mineur en Technologies biomédicales MIN_BIOMED Biomedical technologies minor MIN_BIOMED
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Photonics minor, 2024-2025, Semestre automne Photonics minor, 2024-2025, Autumn semester Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Semestre automne H HIVER Autumn semester H Photonics minor MIN_PHOTONICS Photonics minor MIN_PHOTONICS
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
Photonique (edoc), 2024-2025 Photonics (edoc), 2024-2025 Ecole polytechnique fédérale de Lausanne EPFL Ecole polytechnique fédérale de Lausanne EPFL 2024-2025 Photonique (edoc) EDPO Photonics (edoc) EDPO
optionnel optional
2 Cours Courses Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
1 Exercices Exercises Heure(s) hebdo x 14 semaines Hour(s) per week x 14 weeks H hebdo H hebdo Wagnières Georges 106697
Ingénierie des sciences du vivant SV Life Sciences Engineering SV
839100255 Biomedical optics Biomedical optics 3
Oral Oral Crédit Credits 3 Session hiver Session winter HIV HIV
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